The first cell line we ever tried to image is back and yielding some stunning whole-cell 2D images of the actin network around the nucleus. The glutaraldehyde protocol we have specifically optimized for actin ultrastructure preservation has now been tested on three different mammalian cell lines, all with great results, and should be published as part of an upcoming paper. 

It’s not every day you see detail like that! We are so pleased with how our actin staining protocols are coming along and ongoing tweaks to the scope are improving every image as we go.